He, Death Faces, Fuck-Knuckle and Mother Russia follow Chris to the headquarter of the Justice Forever, helping killing Colonel Stars and wrecking the base of operation. After a few crime and assault on Katie Deauxma, he hire some guys to set up the Lair and plan their attack at Time Square.
It's possible Luigi died in battle or arrested by authorities.
- Luigi is later replaced by his film counterpart, Javier.
- Despite dressing up as like a stereotypical mad scientist when doing supervillain activities, he is never seen doing anything directly science-related.